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CAS No. 15537-72-1 | 1，1-DIMETHYLBIGUANIDE HYDROCHLORIDE

CAS No. 15537-72-1 | 1，1-DIMETHYLBIGUANIDE HYDROCHLORIDE

Name: 1，1-DIMETHYLBIGUANIDE HYDROCHLORIDE CAS No.15537-72-1 MF:C4H11N5 MW:165.62 Purity:99% Package: 5g,25g,200g,500g,1kg Worldwide Delivery

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Product introduction

Introduction and application of CAS No. 15537-72-1 | 1，1-DIMETHYLBIGUANIDE HYDROCHLORIDE

Synonyms:1-Dimethylbiguanide Hydrochloride-D6

Specification:

ITEMS	SPECIFICATION
CAS	15537-72-1
MF	C4H11N5
MW	165.62
Melting point	223-226 °C

Introduction:

Metformin hydrochloride is a hypoglycemic drug that can reduce fasting and postprandial hyperglycemia in patients with type 2 diabetes. Hbalc can be reduced by 1% to 2%. The mechanism of metformin hydrochloride lowering blood sugar may be:

① Increase the sensitivity of peripheral tissues to insulin, increase insulin Mediated glucose utilization.

② Increase the utilization of glucose by non-insulin-dependent tissues, such as brain, blood cells, renal medulla, intestine, skin, etc.

③Inhibit hepatic gluconeogenesis and reduce hepatic glucose output.

④ Inhibits glucose uptake by intestinal wall cells.

⑤ Inhibit the biosynthesis and storage of cholesterol, and reduce blood triglyceride and total cholesterol levels. Different from the effect of insulin, this product does not promote fat synthesis and has no obvious hypoglycemic effect on normal people. It generally does not cause hypoglycemia when used alone for type II diabetes.

resolve resolution:

The synthesis method of metformin hydrochloride is as follows:

(1) Salt formation stage: In the reaction kettle, add dimethylamine aqueous solution, and under low temperature conditions, add hydrochloric acid aqueous solution dropwise to obtain dimethylamine hydrochloride aqueous solution;

(2) Salt evaporation stage: Dimethylamine hydrochloride aqueous solution is distilled under reduced pressure, and water is evaporated to obtain dimethylamine hydrochloride solid;

(3) Condensation stage: Add DMF, toluene and dicyandiamide, heat the reaction to obtain metformin hydrochloride, cool down and filter to obtain metformin hydrochloride crystals, and dry the drying material to obtain white metformin hydrochloride.

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Package: 5g,25g,200g,500g,1kg